(S,Sp)-tBu-Phosferrox is widely used in asymmetric catalysis, particularly in enantioselective hydrogenation reactions. It is highly effective in producing chiral compounds, which are essential in the pharmaceutical industry for the synthesis of active pharmaceutical ingredients (APIs). This ligand is also employed in the production of fine chemicals, where high selectivity and efficiency are required. Its robust performance in various catalytic processes makes it a valuable tool in organic synthesis, enabling the creation of complex molecules with precise stereochemistry. Additionally, it finds applications in academic research for developing new catalytic methodologies and exploring reaction mechanisms.