FTI-2148 diTFA is primarily used in research settings to study the inhibition of farnesyltransferase, an enzyme involved in the post-translational modification of proteins. This chemical is particularly valuable in cancer research, as farnesyltransferase plays a critical role in the activation of certain oncoproteins, such as Ras. By inhibiting this enzyme, FTI-2148 diTFA helps researchers investigate potential therapeutic strategies for cancers driven by Ras mutations. Additionally, it is utilized in biochemical assays to understand the signaling pathways and cellular processes regulated by farnesylated proteins. Its application extends to studying the effects of farnesyltransferase inhibition on cell proliferation, differentiation, and apoptosis, providing insights into targeted cancer therapies.