FTI 276 is primarily used in research to study the role of farnesyltransferase in cellular processes. It is a potent inhibitor of this enzyme, which plays a critical role in the post-translational modification of proteins, particularly Ras proteins. By inhibiting farnesyltransferase, FTI 276 helps researchers investigate the signaling pathways involved in cell growth, differentiation, and survival. This makes it a valuable tool in cancer research, as aberrant Ras signaling is often implicated in tumor development and progression. Additionally, FTI 276 is used to explore potential therapeutic strategies targeting Ras-related diseases, including certain types of cancers. Its application extends to understanding the broader implications of protein prenylation in cellular function and disease mechanisms.