Diethyl glutaconate is widely used in organic synthesis as a versatile building block for the preparation of various chemical compounds. It serves as a key intermediate in the production of pharmaceuticals, particularly in the synthesis of active pharmaceutical ingredients (APIs) that require complex ester functionalities. The compound is also employed in the development of fine chemicals and specialty materials, where its reactivity allows for the creation of diverse molecular structures. Additionally, it finds application in polymer chemistry, where it acts as a monomer or cross-linking agent to modify the properties of polymers, enhancing their flexibility, durability, or other characteristics. In research, it is utilized in the study of reaction mechanisms and the development of new synthetic methodologies.