Tert-Butyl 4,4,4-Trifluorobut-2-Enoate
98%
Reagent
Code: #243723
CAS Number
78762-71-7
blur_circular Chemical Specifications
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Molecular Information
Weight
196.17 g/mol
Formula
C₈H₁₁F₃O₂
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Storage & Handling
Storage
Room temperature
description Product Description
Used as a key intermediate in the synthesis of fluorinated organic compounds, particularly in pharmaceutical and agrochemical industries. Its α,β-unsaturated ester structure with a trifluoromethyl group enables Michael addition reactions and other conjugate additions, facilitating the construction of complex fluorinated molecules. The tert-butyl ester group offers stability during multi-step syntheses and can be easily deprotected under mild acidic conditions. It is especially valuable in medicinal chemistry for introducing fluorine-containing motifs that enhance metabolic stability, lipophilicity, and bioavailability of drug candidates.
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