Ethyl 2,2-Difluoro-2-(4-fluorophenyl)acetate
90%
Reagent
Code: #183824
CAS Number
175543-23-4
blur_circular Chemical Specifications
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Molecular Information
Weight
218.17 g/mol
Formula
C₁₀H₉F₃O₂
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Registry Numbers
MDL Number
MFCD12404934
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Storage & Handling
Storage
2-8℃
description Product Description
Used as a key intermediate in the synthesis of fluorinated pharmaceuticals, particularly in the production of certain antifungal and anti-inflammatory agents. Its structure allows for enhanced metabolic stability and bioavailability in drug candidates. Commonly employed in medicinal chemistry for constructing difluorinated building blocks that improve pharmacokinetic properties. Also utilized in the development of agrochemicals where fluorine substitution increases activity and environmental persistence. Suitable for cross-coupling reactions and nucleophilic substitutions due to the activated ester and electron-withdrawing fluorine groups.
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