tert-Butyl 2-bromo-4-fluoro-3-formylbenzoate
99%
Reagent
Code: #141955
Alias
Benzoicacid,2-broMo-4-fluoro-3-forMyl-,1,1-diMethylethylester;tert-Butyl2-bromo-4-fluoro-3-formylbenzoatChemicalbooke;2-Bromo-4-fluoro-3-formylbenzoicacidtert-butylester;2-Bromo-4-fluoro-3-formylbenzoicacidtert-butyleste
CAS Number
1203662-35-4
blur_circular Chemical Specifications
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Molecular Information
Weight
303.13 g/mol
Formula
C₁₂H₁₂BrFO₃
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Registry Numbers
MDL Number
MFCD22628076
thermostat
Physical Properties
Boiling Point
342.0±42.0 °C(Predicted)
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Storage & Handling
Density
1.450±0.06 g/cm3(Predicted)
Storage
2-8°C
description Product Description
Used as a key intermediate in the synthesis of pharmaceuticals, particularly in the development of fluorinated active pharmaceutical ingredients (APIs). Its aldehyde and bromo functional groups allow for selective cross-coupling reactions and condensation processes, making it valuable in constructing complex aromatic frameworks. Commonly employed in the preparation of kinase inhibitors and anti-inflammatory agents. The tert-butyl ester group acts as a protecting group, enabling controlled deprotection during multi-step syntheses. Also utilized in agrochemical research for building fluorinated building blocks with enhanced metabolic stability.
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