Used in perfumery for its fresh, floral, and slightly citrusy scent, neroli oil is a key ingredient in high-end fragrances and colognes. It blends well with other essential oils and is often used in soaps, lotions, and cosmetics for its pleasant aroma and skin-soothing properties. In aromatherapy, it is valued for its calming effects, helping to reduce stress, anxiety, and promote better sleep. It is also used in some natural skincare products for its antiseptic, anti-inflammatory, antibacterial, and antifungal qualities, beneficial for treating acne, improving skin tone, and soothing sensitive skin. Due to its soothing nature, it can be found in massage oils and bath products designed for relaxation.

Additionally, neroli oil is used in small amounts in the food and beverage industry to add a natural orange blossom or light floral flavor to products.