1-oxaspiro[2.3]hexane is primarily used in organic synthesis as a versatile building block for creating complex molecular structures. Its unique spirocyclic framework makes it valuable in the development of pharmaceuticals, particularly in the design of drug candidates with specific biological activities. The compound is also employed in the synthesis of agrochemicals, where it contributes to the creation of novel pesticides and herbicides. Additionally, its reactivity and stability under various conditions make it a useful intermediate in the production of fine chemicals and specialty materials. Researchers often utilize it in the study of reaction mechanisms and in the exploration of new synthetic pathways.