AGK-2 is a selective inhibitor of the p300 histone acetyltransferase (HAT), making it a valuable tool in epigenetic research. It is primarily used to study the role of p300 in gene expression, cell proliferation, and differentiation. By inhibiting p300 activity, AGK-2 has shown potential in suppressing the growth of certain cancer cells, particularly in models of leukemia and solid tumors. Researchers use AGK-2 to probe the involvement of acetylation in signaling pathways linked to inflammation, apoptosis, and DNA repair. Its application extends to preclinical studies exploring novel cancer therapies, where modulation of epigenetic regulators is a key strategy. Due to its cell permeability and specificity, AGK-2 is widely used in cellular assays to dissect HAT-dependent mechanisms.