GSK-J2 sodium salt is primarily utilized in biochemical research to study the role of histone demethylases, particularly KDM6A and KDM6B, in cellular processes. It serves as a potent inhibitor of these enzymes, enabling researchers to investigate their impact on gene expression, cell differentiation, and development. This compound is particularly valuable in cancer research, as it helps elucidate the mechanisms by which histone demethylases contribute to tumorigenesis and cancer progression. Additionally, GSK-J2 sodium salt is employed in studies focused on stem cell biology and epigenetic regulation, providing insights into how chromatin modifications influence cellular identity and function. Its application extends to exploring therapeutic strategies targeting epigenetic enzymes in various diseases.