Sulfatase from Helix pomatia is widely used in biochemical research and diagnostic applications. It plays a crucial role in the hydrolysis of sulfate esters, making it valuable for studying sulfated compounds such as glycosaminoglycans, steroids, and other sulfated metabolites. In clinical diagnostics, it is employed to analyze and quantify sulfated hormones and metabolites in biological samples. Additionally, it is utilized in the preparation of desulfated products for further analysis or use in pharmaceutical research. Its ability to cleave sulfate groups also makes it useful in environmental studies for breaking down sulfated pollutants.