Widely used in medicine to enhance the absorption and dispersion of injected drugs, hyaluronidase breaks down hyaluronic acid in connective tissues, allowing for faster diffusion of fluids and medications. It is commonly added to local anesthetics to improve their spread and effectiveness during surgical or dental procedures. In ophthalmology, it is used during eye surgeries such as cataract removal to facilitate tissue penetration and improve visualization. It also aids in subcutaneous fluid administration (hypodermoclysis), especially in patients where intravenous access is difficult. Additionally, hyaluronidase is used to treat infiltration or extravasation of IV fluids and certain chemotherapeutic agents, helping to reduce tissue damage. In aesthetic medicine, it serves as a reversal agent for hyaluronic acid-based dermal fillers, allowing correction of overcorrection or complications like vascular occlusion.