Used in molecular biology for the selective degradation of double-stranded and single-stranded DNA, particularly in removing DNA from RNA preparations to prevent contamination. Commonly applied in protocols requiring DNA-free RNA samples, such as RT-PCR and transcriptome analysis. Also utilized in apoptosis research to study DNA fragmentation, as it functions optimally in acidic environments like lysosomes. Its ability to cleave denatured DNA makes it valuable in chromatin digestion and nucleic acid purification workflows.