(S)-(Rp)-PPFA is a chiral ferrocene-based phosphine ligand used primarily in asymmetric catalysis within organic chemistry. It serves as a key reagent in transition-metal-catalyzed reactions, such as palladium-catalyzed cross-coupling processes (e.g., Suzuki-Miyaura and Heck reactions), where it imparts high enantioselectivity to produce chiral molecules. This specialty chemical is invaluable for synthesizing enantiomerically pure compounds essential in pharmaceuticals, agrochemicals, and fine chemicals. Its unique structure enables efficient chiral induction, facilitating the development of stereoselective synthetic methodologies and supporting advancements in drug discovery and material science.