Tubastatin A trifluoroacetic acid salt is primarily used as a selective HDAC6 inhibitor in research applications. It is widely employed in studying epigenetic regulation and its role in various diseases, particularly cancer and neurodegenerative disorders. Researchers utilize it to investigate the effects of HDAC6 inhibition on cell proliferation, apoptosis, and protein aggregation. It is also used in exploring its potential therapeutic benefits in conditions like Alzheimer’s disease, Huntington’s disease, and multiple myeloma. Additionally, it serves as a tool compound in drug discovery programs aimed at developing novel HDAC6-targeting therapies. Its application extends to studying immune modulation, as HDAC6 inhibition has been linked to altered cytokine production and immune cell function.