SC-560
10mM in DMSO
Reagent
Code: #234101
CAS Number
188817-13-2
blur_circular Chemical Specifications
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Molecular Information
Weight
352.74 g/mol
Formula
C₁₇H₁₂ClF₃N₂O
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Registry Numbers
MDL Number
MFCD02179214
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Storage & Handling
Storage
-20°C
description Product Description
SC-560 is a selective inhibitor of cyclooxygenase-1 (COX-1), an enzyme involved in the production of prostaglandins that mediate inflammation, pain, and platelet aggregation. It is primarily used in research settings to study the role of COX-1 in various physiological and pathological processes. By specifically inhibiting COX-1 without affecting COX-2, SC-560 helps scientists differentiate the contributions of each isoform in models of inflammation, cardiovascular function, and gastrointestinal integrity. It has been utilized in preclinical studies to investigate thrombosis, where COX-1 derived thromboxane plays a key role in platelet activation. Additionally, SC-560 has been applied in studies exploring the protective effects of COX-1 inhibition in certain cancers and neurodegenerative conditions, providing insights into potential therapeutic pathways. Due to its research-focused use, it is not employed as a clinical drug but remains a valuable tool in pharmacological and biochemical research.
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