Ro 48-8071

98%

Reagent Code: #230388
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CAS Number 161582-11-2

blur_circular Chemical Specifications

scatter_plot Molecular Information
Weight 448.37 g/mol
Formula C₂₃H₂₇BrFNO₂
inventory_2 Storage & Handling
Storage 2-8℃

description Product Description

Used primarily in biochemical and pharmacological research, this compound acts as a potent inhibitor of squalene synthase, a key enzyme in the cholesterol biosynthesis pathway. By inhibiting this enzyme, it effectively reduces cholesterol production in cells, making it a valuable tool for studying lipid metabolism and developing potential treatments for hypercholesterolemia and related cardiovascular diseases. It has been utilized in in vitro and in vivo studies to explore the consequences of blocked cholesterol synthesis, including effects on cell membrane integrity, steroid hormone production, and liver function. Additionally, due to its ability to lower cholesterol without affecting coenzyme Q or dolichol synthesis, it offers a selective mechanism that helps researchers understand the specific roles of cholesterol in biological systems. Preliminary research also suggests potential anti-cancer applications by disrupting sterol synthesis in abnormal cell proliferation, though its application remains largely confined to preclinical research settings.

shopping_cart Available Sizes & Pricing

Size Availability Unit Price Quantity
inventory 5mg
10-20 days ฿4,890.00
inventory 10mg
10-20 days ฿9,250.00
inventory 50mg
10-20 days ฿43,210.00

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