2,6-Dimethyl-4-(3-methyl-1H-indazol-5-yl)-1,4-dihydropyridine-3,5-dicarbonitrile(BAY-474)
98%
Reagent
Code: #178206
CAS Number
1033767-86-0
blur_circular Chemical Specifications
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Molecular Information
Weight
289.33 g/mol
Formula
C₁₇H₁₅N₅
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Storage & Handling
Storage
-20°C
description Product Description
Used in research as a potent and selective inhibitor of the enzyme soluble epoxide hydrolase (sEH), this compound plays a key role in studies related to inflammation, pain, and cardiovascular diseases. By inhibiting sEH, it helps stabilize endogenous epoxy fatty acids, which have anti-inflammatory and vasoprotective effects. It is commonly applied in preclinical models to investigate conditions such as hypertension, neuropathic pain, and metabolic syndrome. Its ability to modulate lipid signaling pathways makes it a valuable tool in pharmacological studies aiming to develop new therapies for chronic inflammatory and vascular disorders.
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