5-Cyclopropyl-2-[4-(4-fluoro-phenoxy)-phenyl]-6-[(2-hydroxy-ethyl)-methanesulfonyl-amino]-benzofuran-3-carboxylic acid methylamide
≥95%
Reagent
Code: #162951
CAS Number
1179985-50-2
blur_circular Chemical Specifications
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Molecular Information
Weight
538.59 g/mol
Formula
C₂₈H₂₇FN₂O₆S
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Storage & Handling
Density
1.388±0.06 g/cm3(Predicted)
Storage
Room temperature
description Product Description
Used in pharmaceutical research as a potent and selective inhibitor of soluble epoxide hydrolase (sEH), this compound plays a key role in modulating biological pathways involved in inflammation, pain, and cardiovascular regulation. Its primary application lies in the development of therapies for inflammatory diseases, neuropathic pain, hypertension, and metabolic disorders. By inhibiting sEH, it increases levels of endogenous epoxyeicosatrienoic acids (EETs), which have protective effects in vascular and renal systems. It is also employed as a reference compound in pharmacokinetic and pharmacodynamic studies due to its favorable metabolic stability and bioavailability in preclinical models.
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