Used in research to block the activity of the CREB (cAMP response element-binding) protein, which plays a key role in cell signaling, gene expression, and survival pathways. It is studied in cancer research for its potential to suppress tumor growth, particularly in cancers where CREB is overactive, such as certain types of leukemia, prostate cancer, and breast cancer. It helps scientists understand how CREB influences cell proliferation and resistance to therapy. Also used in neuroscience research to investigate memory formation and neuronal plasticity, as CREB is involved in learning and memory processes. Its inhibitory action allows researchers to dissect signaling pathways in cellular and animal models.