Used as an inhibitor of cyclic GMP-AMP synthase (cGAS), CY-09 suppresses the cGAS-STING signaling pathway, which plays a key role in innate immune responses. It is widely applied in immunological research to study inflammation, autoimmune diseases, and antiviral defense mechanisms. CY-09 has shown potential in reducing excessive inflammation in cellular and animal models, making it a valuable tool for investigating conditions such as lupus, arthritis, and other interferonopathies. Additionally, it is used in cancer research to modulate immune activation and understand tumor microenvironment interactions.