Cambinol
10mM in DMSO
Reagent
Code: #157707
CAS Number
14513-15-6
blur_circular Chemical Specifications
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Molecular Information
Weight
360.43 g/mol
Formula
C₂₁H₁₆N₂O₂S
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Registry Numbers
MDL Number
MFCD09057543
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Storage & Handling
Storage
-20°C
description Product Description
Cambinol is primarily studied for its biological activity in inhibiting specific enzymes involved in cellular regulation. It shows promise as an inhibitor of histone acetyltransferases (HATs), particularly the p300 and PCAF enzymes, which play key roles in gene expression and cell cycle control. Due to this inhibitory action, cambinol has been investigated in cancer research for its potential to suppress tumor growth and induce apoptosis in various cancer cell lines.
It has demonstrated antiproliferative effects in models of lymphoma, melanoma, and other malignancies. Additionally, cambinol exhibits antioxidant properties and has been explored for neuroprotective applications in models of oxidative stress-related diseases. Its ability to modulate cellular redox status contributes to its observed protective effects in neuronal cells.
Research also suggests cambinol may interfere with quorum sensing in certain bacteria, indicating possible antimicrobial or anti-biofilm applications. However, these effects are still under early investigation. Overall, cambinol remains a tool compound in biochemical research with potential therapeutic relevance in oncology and neurodegenerative conditions.
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