CADD522 is primarily used in biomedical research as a potent inhibitor of iron-dependent cell death pathways, particularly ferroptosis. It has shown promise in protecting cells from oxidative stress-induced damage by modulating key signaling pathways involved in lipid peroxidation and mitochondrial function. Due to its ability to cross the blood-brain barrier, CADD522 is being explored for neuroprotective applications in models of neurodegenerative diseases such as Parkinson’s and Alzheimer’s. Additionally, it is used as a tool compound in cancer research to study the role of iron metabolism in tumor cell survival and response to therapy. Its selectivity and potency make it valuable in probing cellular mechanisms related to redox balance and cell death regulation.