Used as a potent and selective inhibitor of protein kinase C (PKC) in cellular signaling research. It helps modulate PKC-mediated pathways involved in cell proliferation, differentiation, and apoptosis. Commonly applied in studies related to cancer, neurodegenerative diseases, and inflammation to assess the role of PKC isoforms. Its acetate form improves solubility for in vitro assays. Frequently used in pharmacological experiments to block PKC activity and investigate downstream effects in neuronal and immune cells.