3-Aminobenzamide
10mM in DMSO
Reagent
Code: #133935
CAS Number
3544-24-9
blur_circular Chemical Specifications
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Molecular Information
Weight
136.15 g/mol
Formula
C₇H₈N₂O
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Registry Numbers
EC Number
222-586-9
MDL Number
MFCD00007989
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Physical Properties
Melting Point
115-116 °C(lit.)
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Storage & Handling
Storage
-20°C
description Product Description
Used in research as an inhibitor of poly (ADP-ribose) polymerase (PARP), an enzyme involved in DNA repair. This property makes it valuable in studies related to cancer therapy, particularly in enhancing the effects of DNA-damaging agents like radiation and certain chemotherapeutics. It is also applied in cellular and molecular biology to investigate pathways linked to oxidative stress, inflammation, and apoptosis. Due to its ability to cross cell membranes easily, it is favored in experimental models for modulating PARP activity and studying the consequences of its inhibition.
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