NVP-CGM097 sulfate is primarily utilized in the field of oncology research, where it plays a crucial role in targeting specific protein interactions involved in cancer cell proliferation. It is particularly effective in inhibiting the p53-MDM2 interaction, which is a key pathway in regulating tumor suppression. By disrupting this interaction, it helps to reactivate the p53 tumor suppressor protein, thereby inducing apoptosis in cancer cells. This makes it a valuable compound in the development of novel cancer therapies, especially for tumors that are resistant to conventional treatments and those with high MDM2 expression, such as leukemia and soft tissue sarcoma. It is used in preclinical and clinical studies to evaluate its efficacy and safety, and it is currently in clinical trials for potential applications in humans.