D-threo-PPMP is primarily utilized in biochemical research to study and inhibit the activity of glucosylceramide synthase, an enzyme involved in the synthesis of glycosphingolipids. By inhibiting this enzyme, it helps researchers understand the role of glycosphingolipids in cellular processes and their association with diseases such as Gaucher's disease and other lysosomal storage disorders. It is also used in the development of potential therapeutic strategies targeting these conditions. Additionally, D-threo-PPMP serves as a tool in exploring lipid metabolism and its impact on cell signaling and membrane structure.