Used in pharmaceutical research as a chiral intermediate for synthesizing biologically active compounds, particularly in the development of enzyme inhibitors and receptor modulators. Its rigid indane core and functionalized side chains make it valuable for structure-activity relationship studies. The presence of a propargyl group allows for further modification via click chemistry, enabling rapid generation of compound libraries for drug discovery. Commonly employed in the design of protease inhibitors due to the pyrrolidine carboxamide moiety mimicking peptide bonds. The trifluoroacetate salt form enhances solubility and stability during synthetic processing.