Used in cancer research to block the activity of the Skp2 protein, which plays a key role in promoting the degradation of tumor suppressor proteins like p27. By inhibiting Skp2, SKPin C1 helps stabilize p27 and other cell cycle regulators, leading to cell cycle arrest and suppression of tumor growth. It is particularly studied in models of prostate cancer, breast cancer, and lymphoma. Its application allows scientists to explore targeted therapies that restore normal cell cycle control in cancer cells.