SCH66336
10mM in DMSO
Reagent
Code: #233829
CAS Number
193275-84-2
blur_circular Chemical Specifications
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Molecular Information
Weight
638.820 g/mol
Formula
C₂₇H₃₁Br₂ClN₄O₂
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Registry Numbers
MDL Number
MFCD06795138
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Storage & Handling
Storage
-20°C
description Product Description
Used in research as a potent inhibitor of farnesyltransferase, an enzyme involved in the post-translational modification of proteins such as Ras. By blocking farnesyltransferase, it prevents the activation of oncogenic Ras proteins, which are implicated in various cancers. Investigated for its antitumor activity in preclinical studies, particularly in cancers with Ras mutations, including pancreatic, lung, and colon cancers. Also used as a tool compound to study signaling pathways related to cell growth and apoptosis.
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