(S)-3-(1H-Indol-3-yl)-N-(4-(4-methoxyphenyl)thiazol-2-yl)-2-(4-methylphenylsulfonamido)propanamide
≥98%
Reagent
Code: #233344
CAS Number
2421117-98-6
blur_circular Chemical Specifications
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Molecular Information
Weight
546.66 g/mol
Formula
C₂₈H₂₆N₄O₄S₂
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Storage & Handling
Density
1.381±0.06 g/cm3(Predicted)
Storage
Room temperature, light-proof, inert gas
description Product Description
Used in pharmaceutical research as a potent and selective inhibitor of indoleamine 2,3-dioxygenase 1 (IDO1), an enzyme involved in immune regulation. It modulates the immune response by blocking the metabolism of tryptophan along the kynurenine pathway, thereby preventing immunosuppression in the tumor microenvironment. Investigated for potential use in cancer immunotherapy, particularly in combination with other immune checkpoint inhibitors. Also employed as a biochemical tool to study IDO1 enzyme activity and pathway dynamics in cellular and animal models.
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