4-(4-(((2R,3R)-3-(3-Carbamimidoylbenzyl)-4-Methoxy-4-Oxobutan-2-Yl)Carbamoyl)Phenyl)Pyridine 1-Oxide Hydrochloride
98%
science Other reagents with same CAS 409081-12-5
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Used in pharmaceutical research as a selective inhibitor of protein arginine methyltransferase 5 (PRMT5), an enzyme involved in epigenetic regulation. Shows potential in oncology for targeting cancer cells with aberrant PRMT5 activity, particularly in hematological malignancies and certain solid tumors. Its structure allows for enhanced solubility and cellular permeability, making it suitable for in vitro and in vivo studies. Also employed as a biochemical tool to investigate arginine methylation pathways and their role in gene expression and signal transduction.
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