Used in research for its ability to inhibit gamma-secretase, an enzyme involved in the processing of amyloid precursor protein. This property makes it relevant in studies targeting Alzheimer’s disease, where reducing amyloid beta production is a therapeutic goal. Also investigated in oncology research, particularly in cancers dependent on Notch signaling pathways, such as certain types of leukemia and solid tumors. Its role in blocking Notch activation has shown potential in slowing tumor growth and improving treatment responses in preclinical models. Primarily used in laboratory and clinical trial settings to evaluate efficacy and safety in targeted therapies.