Rucaparib (AG-014699, PF-01367338)
10mM in DMSO
Reagent
Code: #229605
CAS Number
459868-92-9
science Other reagents with same CAS 459868-92-9
blur_circular Chemical Specifications
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Molecular Information
Weight
421.36 g/mol
Formula
C₁₉H₁₈FN₃O·H₃PO₄
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Registry Numbers
MDL Number
MFCD17010269
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Storage & Handling
Storage
-20°C
description Product Description
Used in the treatment of ovarian cancer, particularly in patients with BRCA gene mutations. It is also approved for maintenance therapy in recurrent epithelial ovarian, fallopian tube, or primary peritoneal cancer. Works by inhibiting PARP enzymes, which helps prevent cancer cells from repairing their DNA, leading to cell death. Employed in advanced stages of cancer when other treatments have failed. Commonly used in combination with other chemotherapeutic agents or as a standalone oral therapy.
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