2-(4-(3-((4-Oxo-3,4-dihydrophthalazin-1-yl)methyl)benzoyl)piperazin-1-yl)nicotinonitrile

98%

Reagent Code: #222477
fingerprint
CAS Number 1825345-33-2

science Other reagents with same CAS 1825345-33-2

blur_circular Chemical Specifications

scatter_plot Molecular Information
Weight 450.5 g/mol
Formula C₂₆H₂₂N₆O₂
inventory_2 Storage & Handling
Storage Room temperature, seal, dry

description Product Description

Used in pharmaceutical research as a potent and selective inhibitor of poly (ADP-ribose) polymerase (PARP), particularly PARP-1 and PARP-2. It is investigated for its role in cancer therapy, especially in tumors with deficiencies in DNA repair pathways such as BRCA-mutated breast and ovarian cancers. The compound enhances the cytotoxic effects of DNA-damaging agents and shows promise in synthetic lethality approaches, where it selectively targets cancer cells while sparing normal tissues. It has been explored in preclinical models for its antitumor activity and pharmacokinetic profile, supporting its development as part of targeted oncology treatments.

shopping_cart Available Sizes & Pricing

Size Availability Unit Price Quantity
inventory 100mg
10-20 days ฿36,580.00
inventory 250mg
10-20 days ฿54,820.00

Cart

No products

Subtotal: 0.00
Total 0.00 THB
2-(4-(3-((4-Oxo-3,4-dihydrophthalazin-1-yl)methyl)benzoyl)piperazin-1-yl)nicotinonitrile
No image available

Used in pharmaceutical research as a potent and selective inhibitor of poly (ADP-ribose) polymerase (PARP), particularly PARP-1 and PARP-2. It is investigated for its role in cancer therapy, especially in tumors with deficiencies in DNA repair pathways such as BRCA-mutated breast and ovarian cancers. The compound enhances the cytotoxic effects of DNA-damaging agents and shows promise in synthetic lethality approaches, where it selectively targets cancer cells while sparing normal tissues. It has been exp

Used in pharmaceutical research as a potent and selective inhibitor of poly (ADP-ribose) polymerase (PARP), particularly PARP-1 and PARP-2. It is investigated for its role in cancer therapy, especially in tumors with deficiencies in DNA repair pathways such as BRCA-mutated breast and ovarian cancers. The compound enhances the cytotoxic effects of DNA-damaging agents and shows promise in synthetic lethality approaches, where it selectively targets cancer cells while sparing normal tissues. It has been explored in preclinical models for its antitumor activity and pharmacokinetic profile, supporting its development as part of targeted oncology treatments.

Mechanism -
Appearance -
Longevity -
Strength -
Storage -
Shelf Life -
Allergen(s) -
Dosage (Range) -
Dosage (Per Day) -
Mix Method -
Heat Resistance -
Stable in pH range -
Solubility -
Product Types -
INCI -

Purchase History for

Loading purchase history...