N-methyl-4-oxo-1,4-dihydropyridine-3-carboxamide
95%
Reagent
Code: #218396
CAS Number
3128-29-8
blur_circular Chemical Specifications
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Molecular Information
Weight
152.1506 g/mol
Formula
C₇H₈N₂O₂
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Registry Numbers
MDL Number
MFCD2613204
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Physical Properties
Boiling Point
382.2 °C at 760 mmHg
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Storage & Handling
Storage
2-8°C
description Product Description
Used as a key intermediate in the synthesis of pharmaceutical agents, particularly in the development of nicotinamide phosphoribosyltransferase (NAMPT) inhibitors. These inhibitors are under investigation for their potential in cancer therapy due to their ability to disrupt NAD+ biosynthesis in tumor cells. The compound’s structure supports derivatization at the carboxamide and dihydropyridone moieties, enabling optimization of potency and selectivity in drug candidates. It is also employed in medicinal chemistry research to explore structure-activity relationships in metabolic pathway modulators.
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