N-(4-(4-Acetamidophenyl)thiazol-2-yl)-1-(2,3-dihydrobenzo[b][1,4]dioxin-6-yl)-5-oxopyrrolidine-3-carboxamide
98%
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description Product Description
Used in pharmaceutical research as a potent and selective inhibitor of soluble epoxide hydrolase (sEH), an enzyme involved in the metabolism of epoxyeicosatrienoic acids (EETs). By inhibiting sEH, this compound helps maintain higher levels of EETs, which have anti-inflammatory, analgesic, and vasodilatory effects. It is investigated for potential therapeutic applications in pain management, particularly neuropathic and inflammatory pain, as well as in cardiovascular diseases such as hypertension and atherosclerosis. Its structure allows for good metabolic stability and blood-brain barrier penetration, making it suitable for central nervous system-related studies. Also employed as a lead compound in the development of new sEH inhibitors with improved pharmacokinetic profiles.
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