N-(4-(4-Acetamidophenyl)thiazol-2-yl)-1-(2,3-dihydrobenzo[b][1,4]dioxin-6-yl)-5-oxopyrrolidine-3-carboxamide

98%

Reagent Code: #215644
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CAS Number 790237-66-0

blur_circular Chemical Specifications

scatter_plot Molecular Information
Weight 478.52 g/mol
Formula C₂₄H₂₂N₄O₅S
inventory_2 Storage & Handling
Density 1.454±0.06 g/cm3(Predicted)
Storage 2-8°C, sealed, dry

description Product Description

Used in pharmaceutical research as a potent and selective inhibitor of soluble epoxide hydrolase (sEH), an enzyme involved in the metabolism of epoxyeicosatrienoic acids (EETs). By inhibiting sEH, this compound helps maintain higher levels of EETs, which have anti-inflammatory, analgesic, and vasodilatory effects. It is investigated for potential therapeutic applications in pain management, particularly neuropathic and inflammatory pain, as well as in cardiovascular diseases such as hypertension and atherosclerosis. Its structure allows for good metabolic stability and blood-brain barrier penetration, making it suitable for central nervous system-related studies. Also employed as a lead compound in the development of new sEH inhibitors with improved pharmacokinetic profiles.

shopping_cart Available Sizes & Pricing

Size Availability Unit Price Quantity
inventory 5mg
10-20 days ฿10,430.00
inventory 10mg
10-20 days ฿17,740.00
inventory 25mg
10-20 days ฿35,460.00

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