MS1943 is primarily used as a selective inhibitor in epigenetic research, specifically targeting protein arginine methyltransferase 5 (PRMT5). It is employed in studies related to cancer biology due to PRMT5's role in regulating gene expression and cell proliferation. By inhibiting PRMT5 activity, MS1943 helps researchers investigate the downstream effects on cellular processes such as splicing, transcription, and DNA repair. Its application is especially valuable in identifying potential therapeutic targets in hematological and solid tumors. Additionally, MS1943 serves as a tool compound for validating PRMT5-dependent pathways in cellular models, aiding in the development of more advanced inhibitors for clinical use.