KDM4D-IN-1 is a selective inhibitor of the KDM4D lysine demethylase enzyme, which plays a role in epigenetic regulation by removing methyl groups from histone proteins. Its primary application lies in epigenetic research, where it is used to probe the biological functions of KDM4D in gene expression, cell differentiation, and chromatin remodeling. This compound has shown potential in cancer research due to the involvement of KDM4D in tumor progression and genomic instability. By inhibiting KDM4D, KDM4D-IN-1 can reactivate silenced tumor suppressor genes and impair the growth of certain cancer cells, making it a valuable tool in developing targeted oncology therapies. It is also used in stem cell studies to modulate epigenetic states and improve reprogramming efficiency in induced pluripotent stem cells. Due to its specificity, KDM4D-IN-1 helps researchers dissect the roles of individual demethylases in complex cellular processes, supporting drug discovery and mechanistic studies in epigenetics.