Indeno[1,2-e][1,3,4]oxadiazine-4a(3H)-carboxylic acid, 7-chloro-2,5-dihydro-2-[[(methoxycarbonyl)[4-(trifluoromethoxy)phenyl]amino]carbonyl]-, methyl ester, (4aR)-

≥95%

Reagent Code: #198720
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CAS Number 185608-75-7

blur_circular Chemical Specifications

scatter_plot Molecular Information
Weight 527.8345 g/mol
Formula C₂₂H₁₇ClF₃N₃O₇
thermostat Physical Properties
Boiling Point 571.4±60.0 °C(Predicted)
inventory_2 Storage & Handling
Density 1.53±0.1 g/cm3(Predicted)
Storage 2-8°C

description Product Description

Used as a key intermediate in the synthesis of potent PARP (poly ADP-ribose polymerase) inhibitors, this compound plays a critical role in the development of targeted cancer therapies. Its structure enables high binding affinity to the PARP enzyme, making it valuable in creating drugs that selectively inhibit DNA repair in cancer cells, particularly in BRCA-mutated tumors. It is employed in pharmaceutical research to develop analogs with improved metabolic stability and bioavailability. The compound's functional groups allow for further chemical modifications, facilitating structure-activity relationship studies during drug optimization.

shopping_cart Available Sizes & Pricing

Size Availability Unit Price Quantity
inventory 25mg
10-20 days ฿137,600.00
inventory 10mg
10-20 days ฿67,200.00

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