Used in research to inhibit protein prenylation, specifically blocking geranylgeranyltransferase I (GGTase-I), which plays a role in the post-translational modification of certain proteins involved in cell signaling. This inhibition makes it a valuable tool for studying cancer cell proliferation, tumor growth, and signal transduction pathways, particularly in cancers driven by Ras family oncogenes. Commonly applied in vitro and in animal models to assess the effects of GGTase-I inhibition on cell cycle progression, apoptosis, and metastasis. Also used to differentiate between farnesylation and geranylgeranylation effects in cellular processes.