Used in research for its potent inhibition of nicotinamide phosphoribosyltransferase (NAMPT), an enzyme critical in the biosynthesis of nicotinamide adenine dinucleotide (NAD+). By depleting cellular NAD+ levels, it induces energy collapse and cell death, particularly in cancer cells with high metabolic demands. Shows antitumor activity in preclinical models, especially in hematological malignancies. Investigated for potential use in combination therapies with other anticancer agents due to its ability to sensitize tumor cells to chemotherapy and radiation. Also used as a tool compound to study NAD+ metabolism and its role in aging, inflammation, and neurodegeneration.