Ethyl 2-(3-formyl-4-isobutoxyphenyl)-4-methylthiazole-5-carboxylate
98%
Reagent
Code: #182564
CAS Number
161798-03-4
blur_circular Chemical Specifications
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Molecular Information
Weight
347.43 g/mol
Formula
C₁₈H₂₁NO₄S
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Registry Numbers
MDL Number
MFCD13194811
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Physical Properties
Boiling Point
495.9°C
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Storage & Handling
Storage
2-8°C, inert gas atmosphere
description Product Description
Used as a key intermediate in the synthesis of nonsteroidal anti-inflammatory drugs (NSAIDs), particularly in the development of selective COX-2 inhibitors. Its aldehyde and ester functional groups allow for further chemical modifications, enabling the construction of complex pharmacophores. Commonly employed in medicinal chemistry for structure-activity relationship studies aimed at improving anti-inflammatory potency and reducing gastrointestinal side effects. Also utilized in the preparation of analogs for biological screening in pain and inflammation research.
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