Dp44mT
10mM in DMSO
Reagent
Code: #168728
CAS Number
152095-12-0
blur_circular Chemical Specifications
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Molecular Information
Weight
285.37 g/mol
Formula
C₁₄H₁₅N₅S
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Registry Numbers
MDL Number
MFCD20527329
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Storage & Handling
Storage
-20°C
description Product Description
Used primarily in cancer research due to its potent anti-tumor properties. It acts as a selective chelator of iron and copper, disrupting metal-dependent processes in cancer cells. This leads to inhibition of ribonucleotide reductase, an enzyme critical for DNA synthesis, thereby suppressing tumor growth. Additionally, Dp44mT induces oxidative stress in cancer cells through the generation of reactive oxygen species, promoting apoptosis. Its ability to accumulate preferentially in tumor tissues makes it a promising candidate for targeted cancer therapy. Studies also explore its potential in overcoming drug resistance in chemotherapy.
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