2-[[[4-(Aminoiminomethyl)phenyl]amino]methyl]-N-(3-amino-3-oxopropyl)-1-methyl-N-2-pyridinyl-1H-benzimidazole-5-carboxamide
98%
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Used primarily as a selective inhibitor of protein arginine methyltransferase 1 (PRMT1), this compound plays a key role in epigenetic research. It is utilized in studies related to gene expression, cell differentiation, and cancer progression due to PRMT1's involvement in methylation of histone and non-histone proteins. The compound helps modulate cellular processes linked to leukemia and other cancers, making it valuable in developing targeted cancer therapies. It is also employed in biochemical assays to investigate signaling pathways and protein-protein interactions influenced by arginine methylation. Its high selectivity allows for precise manipulation of PRMT activity in cellular models, supporting drug discovery and mechanistic studies in oncology and epigenetics.
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