Gisadenafil besylate is primarily utilized in the field of medical research, particularly in studies related to erectile dysfunction and pulmonary arterial hypertension. It functions as a potent inhibitor of phosphodiesterase type 5 (PDE5), an enzyme that regulates blood flow in specific tissues. By inhibiting PDE5, it promotes vasodilation and enhances blood circulation, making it a valuable compound for investigating therapeutic interventions for these conditions. Its application extends to preclinical studies, where it helps in understanding the mechanisms of PDE5 inhibition and its effects on vascular and smooth muscle tissues. Researchers also explore its potential in developing new treatments or improving existing therapies for cardiovascular and urological disorders.