DHODH-IN-8 is primarily used in research settings to study its potential as an inhibitor of dihydroorotate dehydrogenase (DHODH), an enzyme involved in the de novo pyrimidine biosynthesis pathway. This makes it a candidate for investigating treatments for diseases where cell proliferation is a key factor, such as cancer and autoimmune disorders. Researchers explore its efficacy in slowing down or stopping the growth of rapidly dividing cells by targeting their nucleotide synthesis. Additionally, it is being evaluated for its role in antiviral therapies, as inhibiting DHODH can disrupt viral replication. Its application is largely confined to preclinical studies, where it helps in understanding the biochemical pathways and potential therapeutic targets.