Used to measure the activity of Human E1/UBAE (ubiquitin-activating enzyme) in biological samples such as cell lysates or tissue extracts. This ELISA kit enables researchers to quantify enzyme activity involved in the ubiquitin-proteasome pathway, which plays a critical role in protein degradation, cell cycle regulation, DNA repair, and signaling processes. It is widely applied in biomedical research to study diseases linked to ubiquitination dysfunction, including cancer, neurodegenerative disorders like Alzheimer's and Parkinson's, and autoimmune conditions. The assay supports drug development by allowing evaluation of inhibitors or activators targeting the ubiquitin activation step. Its high sensitivity and specificity make it suitable for both basic research and therapeutic monitoring in experimental settings.