5-(2-Hydroxyethyl)-3,4-dimethylthiazol-3-ium iodide
97%
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This thiazolium iodide salt serves as a key intermediate in the synthesis of thiamine (vitamin B1) and its analogs, which are essential in biochemical and pharmaceutical applications. Structurally, it features a thiazole ring quaternized at the nitrogen with a methyl group, a methyl substituent at position 4, and a 2-hydroxyethyl group at position 5. Such compounds are utilized in organic synthesis to construct bioactive heterocycles and in research modeling the catalytic mechanisms of thiamine pyrophosphate (TPP) in enzymatic reactions like decarboxylation and benzoin-type condensations. It finds niche applications in medicinal chemistry for developing potential therapeutic agents and as a catalyst in umpolung reactions for carbon-carbon bond formation.
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