5-(2-Hydroxyethyl)-3,4-dimethylthiazol-3-ium iodide

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Reagent Code: #119738
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CAS Number 16311-69-6

blur_circular Chemical Specifications

scatter_plot Molecular Information
Weight 285.15 g/mol
Formula C₇H₁₂INOS
badge Registry Numbers
MDL Number MFCD00011958
thermostat Physical Properties
Melting Point 82-85°C
inventory_2 Storage & Handling
Storage Room temperature, away from light, stored in an inert gas

description Product Description

This thiazolium iodide salt serves as a key intermediate in the synthesis of thiamine (vitamin B1) and its analogs, which are essential in biochemical and pharmaceutical applications. Structurally, it features a thiazole ring quaternized at the nitrogen with a methyl group, a methyl substituent at position 4, and a 2-hydroxyethyl group at position 5. Such compounds are utilized in organic synthesis to construct bioactive heterocycles and in research modeling the catalytic mechanisms of thiamine pyrophosphate (TPP) in enzymatic reactions like decarboxylation and benzoin-type condensations. It finds niche applications in medicinal chemistry for developing potential therapeutic agents and as a catalyst in umpolung reactions for carbon-carbon bond formation.

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Size Availability Unit Price Quantity
inventory 250mg
10-20 days ฿378.00
inventory 5g
10-20 days ฿2,169.00
inventory 1g
10-20 days ฿621.00
inventory 25g
10-20 days ฿6,813.00

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